Moebius Syndrome: disorder present in birth congenital.

Von Graefe first described congenital facial And abducens palsy in 1880 and in 1888 Moebius. A German neurologist behind whom the syndrome was later named.

Moebius syndrome is an infrequent neurological disorder characterized by weakness or paralysis of multiple cranial nerves, most often the 6th abducens and 7th facial nerves. Other cranial nerves are sometimes affected. The disorder is present at birth congenital. 

If the 7th nerve is involved, the individual with Moebius syndrome cannot smile, frown, pucker, the lips, raise the eyebrows, or close the eyelids. If the 6th nerve is affected, the eye cannot turn outward past the midline. 

Other abnormalities include the underdevelopment of the pectoral muscles and defects of the limbs. Moebius syndrome is not progressive. Its exact cause is unknown. It materializes to occur randomly in most cases. However, some cases occur in families suggesting that there may be a genetic component.