Peter's Anomaly: Disease That Cause Corneal Opacity.
15 YO Px with unilateral Peters' anomaly. Px has dense corneal opacity, corectopia with the nasal displacement of pupil, Nystagmus, and Glaucoma. Peters anomaly is one disease in a constellation of diseases that causes corneal opacity due to anterior segment dysgenesis during development.It has been
This is also a one type of the conditions.
15 YO Px with unilateral Peters' anomaly. Px has dense corneal opacity, corectopia with the nasal displacement of pupil, Nystagmus, and Glaucoma. Peters anomaly is one disease in a constellation of diseases that causes corneal opacity due to anterior segment dysgenesis during development.
It has been known above the years as primary mesodermal dysgenesis during development. It has been recognized the years as original mesodermal dysgenesis of the cornea, posterior keratoconus, congenital anterior synechiae, and anterior chamber cleavage syndrome.
Peter's anomaly affects the iris, corneal endothelium, and Descemet's membrane leading to peters type 1. Peters type 2, in addition, will have lens abnormalities and tend to be bilateral. 60% of those with Peter's anomaly are bilateral. In both forms, the pacification of the cornea leads to an amblyogenic effect on a developing infant.
Peter's plus syndrome includes short disproportionate stature, developmental delay, dysmorphic facial features, cardiac, genitourinary, and inner nervous system abnormality. These systemic decisions are seen in up to 60% of patients.
Peter's is also associated with many other ocular pathologies including glaucoma, corectopia, sclerocornea, iris hypoplasia, cataract, ICE syndrome, aniridia, persistent fetal vasculature, iris coloboma, and microcornea.
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